Neonatal Neuromuscular Disorders Congenital Effects

Neuromuscular disorders, such as myasthenia gravis and congenital myasthenic syndromes, affect the muscles, the neuromuscular junction, the nerves (neuropathies), and the anterior horn motor neurons (spinal muscular atrophies). In the neonatal phase, they are present as floppy newborn syndrome with or without contractures. Clinically significant respiratory dysfunction and swallowing issues are frequently accompanied by hypotonia and weakness.

Congenital abnormalities are brought on by issues that emerge throughout the foetus' prenatal development. Parents must be in good health and receive sufficient prenatal care in order to reduce the likelihood of preventable congenital abnormalities. Early identification of the chromosomal and genetic causes of congenital abnormalities has been made possible by improvements in perinatal testing and novel diagnostic techniques. The signs of paediatric neuromuscular disease include

  • Low muscular tone (hypotonia)
  • Delayed motor milestones, such as sluggish walking or a strange gait
  • Muscle atrophy, twitching, rippling, and weakening are all signs of muscle weakness

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